Cryptic crossword clue
Rein in twins, those running the enterprise 11

The most common and most likely answer to this crossword clue is the 11 letter word RINGLEADERS

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "those running the enterprise" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case those running the enterprise = ringleaders.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RINGLEADERS mean?

RINGLEADERS noun
  1. A leader of a group of people, especially an unofficial group.
  2. A person who starts and leads a disturbance (such as a riot), a conspiracy, or a criminal gang.

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