Cryptic crossword clue
Relations with pleasant son involving sweetheart 6

The most common and most likely answer to this crossword clue is the 6 letter word NIECES

I've seen this crossword clue in The Daily Telegraph
N
I
E
C
E
S


Buddy explains!

The straight part
We know that "Relations" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case relations = nieces.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NIECES mean?

NIECES noun
  1. A daughter of one’s sibling, brother-in-law, or sister-in-law; either the daughter of one's brother ("fraternal niece"), or of one's sister ("sororal niece").

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