Cryptic crossword clue
Remain loyal to saint and heartless boy 5-2

The most common and most likely answer to this crossword clue is the 8 letter word STAND-BY

S
T
A
N
D
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B
Y

Buddy explains!

The straight part
We know that "Remain loyal to" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case remain loyal to = stand-by.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does STAND-BY mean?

STAND-BY noun
  1. A state of readiness without immediate involvement; remaining in preparation for (a sudden or unforeseen event or situation).
  2. Sleep mode
  3. (travel) Waiting at the airport in the hope of getting a seat on a flight that is already booked out.
  4. Something that is standard, well-tested, or frequently used.

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