Cryptic crossword clue
Removed fastenings around instrument with full concentration 9

The most common and most likely answer to this crossword clue is the 9 letter word UNDILUTED

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Buddy explains!

The straight part
We know that "with full concentration" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case with full concentration = undiluted.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does UNDILUTED mean?

UNDILUTED adjective
  1. Not diluted or mixed with other substances.
  2. Unadulterated; free from extraneous elements.

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