Cryptic crossword clue
Replacement's a joke, internally team leader's against, to a large extent 13

The most common and most likely answer to this crossword clue is the 13 letter word SUBSTANTIALLY

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Buddy explains!

The straight part
We know that "/ to a large extent" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case / to a large extent = substantially.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SUBSTANTIALLY mean?

SUBSTANTIALLY adverb
  1. In a strong substantial manner; considerably.
  2. To a great extent; in essence; essentially.
  3. Without material qualifications.

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