The most common and most likely answer to this crossword clue is the 5 letter word DRIVE
I've seen this crossword clue in Financial Times
D
R
I
V
E
More clues leading to the result DRIVE
- Head of regiment drills joint force
- Doctor Kildare finally trapping medical equipment in zip
- Direct vehicle right into seedy bar
- Derby game involves four sort of shooting
- Road runs through disreputable place
- Republican in disreputable club shows ambition
- Ambition to succeed? It’ll be a long shot
- Break during noise where screenings take place in US
- Republican’s in dodgy bar to get a shot, of course
- Push the envelope of danger: Boatman’s following
Buddy explains!

The straight part
We know that "a shot, of course" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a shot, of course = drive.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DRIVE mean?
DRIVE noun- Motivation to do or achieve something; ability coupled with ambition.
- Violent or rapid motion; a rushing onward or away; especially, a forced or hurried dispatch of business.
- An act of driving animals forward, as to be captured, hunted etc.
- A sustained advance in the face of the enemy to take a strategic objective.
- A mechanism used to power or give motion to a vehicle or other machine or machine part.
- A trip made in a vehicle (now generally in a motor vehicle).
- A driveway.
- A type of public roadway.
- A place suitable or agreeable for driving; a road prepared for driving.
- Desire or interest.
- An apparatus for reading and writing data to or from a mass storage device such as a disk, as a floppy drive.
- A mass storage device in which the mechanism for reading and writing data is integrated with the mechanism for storing data, as a hard drive, a flash drive.
- A stroke made with a driver.
- A ball struck in a flat trajectory.
- A type of shot played by swinging the bat in a vertical arc, through the line of the ball, and hitting it along the ground, normally between cover and midwicket.
- A straight level shot or pass.
- An offensive possession, generally one consisting of several plays and/ or first downs, often leading to a scoring opportunity.
- A charity event such as a fundraiser, bake sale, or toy drive.
- (retail) A campaign aimed at selling more of a certain product, e.g. by offering a discount.
- An impression or matrix formed by a punch drift.
- A collection of objects that are driven; a mass of logs to be floated down a river.
- To provide an impetus for motion or other physical change, to move an object by means of the provision of force thereto.
- To provide an impetus for a non-physical change, especially a change in one's state of mind.
- To displace either physically or non-physically, through the application of force.
- To cause intrinsic motivation through the application or demonstration of force: to impel or urge onward thusly, to compel to move on, to coerce, intimidate or threaten.
- (especially of animals) To impel or urge onward by force; to push forward; to compel to move on.
- To direct a vehicle powered by a horse, ox or similar animal.
- To cause animals to flee out of.
- To move (something) by hitting it with great force.
- To cause (a mechanism) to operate.
- To operate (a wheeled motorized vehicle).
- To motivate; to provide an incentive for.
- To compel (to do something).
- To cause to become.
- To hit the ball with a drive.
- To travel by operating a wheeled motorized vehicle.
- To convey (a person, etc) in a wheeled motorized vehicle.
- To move forcefully.
- To be moved or propelled forcefully (especially of a ship).
- To urge, press, or bring to a point or state.
- To carry or to keep in motion; to conduct; to prosecute.
- To clear, by forcing away what is contained.
- To dig horizontally; to cut a horizontal gallery or tunnel.
- To put together a drive (n.): to string together offensive plays and advance the ball down the field.
- To distrain for rent.
- To separate the lighter (feathers or down) from the heavier, by exposing them to a current of air.
- To be the dominant party in a sex act.