The most common and most likely answer to this crossword clue is the 3 plus 5 letter word SET ASIDE
I've seen this crossword clue in Financial Times
S
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More clues leading to the result SET ASIDE
- Reserve first of tables in coastal area
- Save time when in grip of terrible disease
- Dismiss special diets containing American drug
- Earmark tourist destination in which trouble kicking off
- Steadies wobbling reserve
- Reserve central hotel in Margate perhaps
- Preserve prepared ideas for reform
- Besides which, I do like to be singing about Tottenham’s first reserve
- Reserve hotel centrally located in coast
- Reject determined to join top class team
Buddy explains!

The straight part
We know that "Reserve" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case reserve = set aside.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SET ASIDE mean?
SET ASIDE noun- Something that is set aside for a specific purpose
- (Britain and Europe) land that has been taken out of agricultural production to reduce crop surpluses
- That has or have been set aside
- Taken out of agricultural production
- Reserved or booked in advance