Cryptic crossword clue
Residence over the pond containing nothing very unpleasant 10

The most common and most likely answer to this crossword clue is the 10 letter word VILLAINOUS

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Buddy explains!

The straight part
We know that "very unpleasant" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case very unpleasant = villainous.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VILLAINOUS mean?

VILLAINOUS adjective
  1. Of, relating to, or appropriate to a villain.
  2. Wicked, offensive, or reprehensible in nature or behaviour; nefarious.

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