Cryptic crossword clue
Respond again to hatless fellows going in to perform again 2-5

The most common and most likely answer to this crossword clue is the 8 letter word RE-ENACT

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Buddy explains!

The straight part
We know that "perform again" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case perform again = re-enact.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RE-ENACT mean?

RE-ENACT verb
  1. To enact again.
  2. To recreate an event, especially a historical battle.

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