Cryptic crossword clue
Response as Charlie goes around the far east – a change in direction 13

The most common and most likely answer to this crossword clue is the 13 letter word REORIENTATION

R
E
O
R
I
E
N
T
A
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N

Buddy explains!

The straight part
We know that "change in direction" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case change in direction = reorientation.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does REORIENTATION mean?

REORIENTATION noun
  1. A new orientation.
  2. The act of changing the direction of something.

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