Cryptic crossword clue
Response of some leaders to Brexit crisis might be put into words as “We’ll just have to lump it” 11

The most common and most likely answer to this crossword clue is the 11 letter word RESIGNATION

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Buddy explains!

The straight part
We know that "&lit/CD-ish double defn?!" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case &lit/cd-ish double defn?! = resignation.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RESIGNATION mean?

RESIGNATION noun
  1. The act of resigning.
  2. A written or oral declaration that one resigns.
  3. State of uncomplaining acceptance in the face of something undesirable but unavoidable.
  4. The form by which a vassal returns the feu into the hands of a superior.

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