The most common and most likely answer to this crossword clue is the 3 plus 4 letter word BIG DEAL
I've seen this crossword clue in The Times
B
I
G
D
E
A
L
More clues leading to the result BIG DEAL
- Response to derisory offer from bishop good in principle
- So what beings periodically give people a hand?
- I beg lad to reform? There’s nothing special about that!
- Important contract
- Bad leg I gathered, who cares?
- Be glad I supply sarcastic response
- Million-dollar contract? I’m not impressed!
- Large place in Kent? I don’t think it’s that wonderful!
- Scornful response from soldier returning holding broken blade? On the contrary
- Like a pimple, for Spooner it’s important
Buddy explains!

The straight part
We know that "Response to derisory offer" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case response to derisory offer = big deal.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.