Cryptic crossword clue
Retired Frenchman into young flesh of the nether regions 8

The most common and most likely answer to this crossword clue is the 8 letter word VENEREAL

I've seen this crossword clue in The Guardian
V
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N
E
R
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Buddy explains!

The straight part
We know that "of the nether regions" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case of the nether regions = venereal.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VENEREAL mean?

VENEREAL adjective
  1. Of or relating to the genitals or sexual intercourse.
  2. Of a disease: sexually transmitted; of or relating to, or adapted to the cure of, a venereal disease.
  3. Pertaining to the astrological influence of the planet Venus; lascivious, lustful.
  4. Of or relating to copper (formerly called Venus by alchemists).

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