Cryptic crossword clue
Retiring Queen and followers prepare for alternative employment 7

The most common and most likely answer to this crossword clue is the 7 letter word RETRAIN

I've seen this crossword clue in The Guardian
R
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T
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A
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Buddy explains!

The straight part
We know that "prepare for alternative employment" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case prepare for alternative employment = retrain.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RETRAIN mean?

RETRAIN verb
  1. To train again; especially, to train or study in a new subject or job

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