Cryptic crossword clue
Retiring saleman’s short trip in car helping to produce sweat 12

The most common and most likely answer to this crossword clue is the 12 letter word PERSPIRATION

I've seen this crossword clue in Independent
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PERSPIRATION mean?

PERSPIRATION noun
  1. The action or process of perspiring.
  2. (by extension) Hard work.
  3. A saline fluid secreted by the sweat glands; sweat.

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