The most common and most likely answer to this crossword clue is the 10 letter word NEOLOGISMS
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Buddy explains!
The straight part
We know that "words like selfie and twerk" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case words like selfie and twerk = neologisms.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does NEOLOGISMS mean?
NEOLOGISMS noun- A word or phrase which has recently been coined; a new word or phrase.
- The act or instance of coining, or uttering a new word.
- The newly coined, meaningless words or phrases of someone with a psychosis, usually schizophrenia.
- The introduction of new doctrine, for example in theology.