Cryptic crossword clue
Ring operates in tough areas 8

The most common and most likely answer to this crossword clue is the 8 letter word CALLUSES

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The cryptic/wordplay part
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CALLUSES mean?

CALLUSES noun
  1. A hardened area of the skin (especially on the foot or hand) caused by repeated friction, wear or use.
  2. The material of repair in fractures of bone; a substance exuded at the site of fracture, which is at first soft or cartilaginous in consistency, but is ultimately converted into true bone and unites the fragments into a single piece.
  3. The new formation over the end of a cutting, before it puts out rootlets.
  4. A shining area on the frons of many species of Tabanomorpha (horse flies and relatives).
CALLUSES verb
  1. To form such hardened tissue.

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