The most common and most likely answer to this crossword clue is the 5 letter word SWEET
I've seen this crossword clue in The Guardian
S
W
E
E
T
More clues leading to the result SWEET
- Angelic group you and I will appear in
- In a group, you and I must be charming
- Delightful hotel accommodation for auditors
- Delightful pudding
- The Speaker's set of rooms is very nice
- Adorable saint swallowing very little
- Gentle 9 or 22 hosting you patronisingly
- Way to embrace little darling
- Rising river swamps women’s course
- Declared set of furniture charming
Buddy explains!

The straight part
We know that "course" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case course = sweet.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SWEET mean?
SWEET noun- The basic taste sensation induced by sugar.
- A confection made from sugar, or high in sugar content; a candy.
- A food eaten for dessert.
- Sweetheart; darling.
- That which is sweet or pleasant in odour; a perfume.
- Sweetness, delight; something pleasant to the mind or senses.
- To sweeten.
- Having a pleasant taste, especially one relating to the basic taste sensation induced by sugar.
- Having a taste of sugar.
- Retaining a portion of sugar.
- Not having a salty taste.
- Having a pleasant smell.
- Not decaying, fermented, rancid, sour, spoiled, or stale.
- Having a pleasant sound.
- Having a pleasing disposition.
- Having a helpful disposition.
- Free from excessive unwanted substances like acid or sulphur.
- Very pleasing; agreeable.
- Doing well; in a good or happy position.
- (followed by on) Romantically fixated, enamoured with, fond of
- Fresh; not salt or brackish.
- Pleasing to the eye; beautiful; mild and attractive; fair.
- In a sweet manner.
- Used as a positive response to good news or information.