The most common and most likely answer to this crossword clue is the 6 letter word DEBASE
I've seen this crossword clue in The Sunday Telegraph
D
E
B
A
S
E
More clues leading to the result DEBASE
- Prostitute and her workplace recalled when on drugs
- Extricating climber from debacle, Matisse is humble
- Lower by shaking sea bed
- Corrupt odd characters in boats in river
- Put a lower value on degree in seed production
- Seabed could become lower
- Contaminate seabed by mistake
- River containing 75 per cent of fish, lower
Buddy explains!

The straight part
We know that "lower" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lower = debase.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DEBASE mean?
DEBASE verb- To lower in character, quality, or value; to degrade.
- To lower in position or rank.
- To lower the value of (a currency) by reducing the amount of valuable metal in the coins.