The most common and most likely answer to this crossword clue is the 10 letter word CIRCUMCISE
I've seen this crossword clue in The Guardian
C
I
R
C
U
M
C
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E
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CIRCUMCISE mean?
CIRCUMCISE verb- To surgically remove the foreskin (prepuce) from a penis (male).
- (sometimes proscribed) To surgically remove the clitoris (clitoridectomy), clitoral hood, or labia (female).