The most common and most likely answer to this crossword clue is the 6 letter word TISSUE
I've seen this crossword clue in The Guardian
T
I
S
S
U
E
More clues leading to the result TISSUE
- Paper's introduction to topical subject
- Paper's publication behind time
- Insubstantial stuff place offered up — seek redress?
- Wipe face on tablecloth, kids!
- Introduction to timely subject in paper?
- Time to put out paper
- Joint publication provides absorbing material
- Roget’s last edition, which forms the basis of culture
- It’s cryptic woman’s paper
- Developing its use in an intricate structure of connected items
Buddy explains!

The straight part
We know that "the basis of culture" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case the basis of culture = tissue.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does TISSUE mean?
TISSUE noun- Thin, woven, gauze-like fabric.
- A fine transparent silk material, used for veils, etc.; specifically, cloth interwoven with gold or silver threads, or embossed with figures.
- A sheet of absorbent paper, especially one that is made to be used as tissue paper, toilet paper or a handkerchief.
- Absorbent paper as material.
- A group of cells similar in origin that function together to do a specific job.
- Web; texture; complicated fabrication; connected series.
- To form tissue of; to interweave.