Cryptic crossword clue
Rogue disheartened by attempt to prosecute again 5

The most common and most likely answer to this crossword clue is the 5 letter word RETRY

R
E
T
R
Y

Buddy explains!

The straight part
We know that "prosecute again" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case prosecute again = retry.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RETRY mean?

RETRY noun
  1. Another attempt.
RETRY verb
  1. To try or attempt again.
  2. To try judicially a second time.

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