Cryptic crossword clue
Roman with space for manufacturing cream cheese 10

The most common and most likely answer to this crossword clue is the 10 letter word MASCARPONE

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "cream cheese" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case cream cheese = mascarpone.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MASCARPONE mean?

MASCARPONE noun
  1. A soft, creamy Italian cheese that is not pressed or aged; often used in desserts.

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