Cryptic crossword clue
Rough and rude treatment for rabies at hospital 7

The most common and most likely answer to this crossword clue is the 7 letter word BEARISH

I've seen this crossword clue in The Guardian
B
E
A
R
I
S
H

Buddy explains!

The straight part
We know that "Rough and rude" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case rough and rude = bearish.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BEARISH mean?

BEARISH adjective
  1. Resembling or likened to a bear, typically in being rough, surly, or clumsy.
  2. (of the price of financial instruments) Characterized by falling prices.
  3. (by extension) Pessimistic about the future.

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