Cryptic crossword clue
Rudeness of men, recipient distraught 12

The most common and most likely answer to this crossword clue is the 12 letter word IMPERTINENCE

I
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Buddy explains!

The straight part
We know that "Rudeness" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case rudeness = impertinence.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does IMPERTINENCE mean?

IMPERTINENCE noun
  1. Lack of pertinence; irrelevance.
  2. An instance of this; a moment of being impertinent.
  3. The fact or character of being out of place; inappropriateness.
  4. Insolence; impudence.

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