The most common and most likely answer to this crossword clue is the 4 letter word SEWN
I've seen this crossword clue in The Times
S
E
W
N
More clues leading to the result SEWN
- Darned report switching sides
- Run up from all directions
- Old nurse squeezing opening of wound to be stitched
- Needled by 28 after swapping sides
- Broadcast newsreels
- Stitched up in news broadcast?
- What’s embroidered and broadcast on air?
- Put together broadcast — broadcast news broadcast
- Stitched together broadcast for the audience
- Darned partners embracing opponents
Buddy explains!

The straight part
We know that "Run up" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case run up = sewn.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SEWN mean?
SEWN verb- To use a needle to pass thread repeatedly through (pieces of fabric) in order to join them together.
- To use a needle to pass thread repeatedly through pieces of fabric in order to join them together.
- Followed by into: to enclose by sewing.