Cryptic crossword clue
Runs off and weds, unclothed and hungry 5

The most common and most likely answer to this crossword clue is the 5 letter word UNFED

I've seen this crossword clue in The Guardian
U
N
F
E
D

Buddy explains!

The straight part
We know that "hungry" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case hungry = unfed.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does UNFED mean?

UNFED noun
  1. A mosquito that has not had a blood meal.
UNFED adjective
  1. Not fed.
  2. Unsupported.

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