Cryptic crossword clue
Runs out of air? Oh dear! 9

The most common and most likely answer to this crossword clue is the 9 letter word DIARRHOEA

I've seen this crossword clue in The Guardian
D
I
A
R
R
H
O
E
A

Buddy explains!

The straight part
We know that "Runs" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case runs = diarrhoea.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DIARRHOEA mean?

DIARRHOEA noun
  1. A gastrointestinal disorder characterized by frequent and very fluid or watery bowel movements.
  2. The watery or very soft excrement that comes from such bowel movements.

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