Cryptic crossword clue
Rye-occupant famously having shut up wife within, one anxious for work to end 12

The most common and most likely answer to this crossword clue is the 13 letter word CLOCK-WATCHER

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Buddy explains!

The straight part
We know that "one anxious for work to end" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one anxious for work to end = clock-watcher.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CLOCK-WATCHER mean?

CLOCK-WATCHER noun
  1. A person who is eager for time to pass (e.g., at work or school), especially when faced with an undesirable task.

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