The most common and most likely answer to this crossword clue is the 6 letter word RAVAGE
I've seen this crossword clue in The Times
R
A
V
A
G
E
More clues leading to the result RAVAGE
- Sack a blackleg, ultimately splitting party
- Destroy resistance, mean, without hesitation
- Sack Virginia during a fit of madness
- Destroy scripture that’s in fashion
- Plunder silver during house party
- Destroy version of Bible in fit of anger
- Storm engulfing a very tiny ruin
- Sack a Government leader in illegal party
- Cause devastation, writing a volume in anger
Buddy explains!

The straight part
We know that "Sack" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sack = ravage.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does RAVAGE mean?
RAVAGE noun- Grievous damage or havoc.
- Depredation or devastation
- To devastate or destroy something.
- To pillage or sack something, to lay waste to something.
- To wreak destruction.