Cryptic crossword clue
Sack cleaner holding up key centre of worship 10

The most common and most likely answer to this crossword clue is the 10 letter word TABERNACLE

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "centre of worship" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case centre of worship = tabernacle.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TABERNACLE mean?

TABERNACLE noun
  1. Any temporary dwelling; a hut, tent, or booth.
  2. The portable tent used before the construction of the temple, where the shekinah (presence of God) was believed to dwell.
  3. (by extension) The Jewish Temple at Jerusalem (as continuing the functions of the earlier tabernacle).
  4. Any portable shrine used in heathen or idolatrous worship.
  5. A sukkah, the booth or 'tabernacle' used during the Jewish Feast of Sukkot.
  6. A small ornamented cupboard or box used for the reserved sacrament of the Eucharist, normally located in an especially prominent place in a Roman Catholic church.
  7. A temporary place of worship, especially a tent, for a tent meeting, as with a venue for revival meetings.
  8. (by extension) Any house of worship; used especially of Mormon churches.
  9. Any abode or dwelling place, or especially the human body as the temporary dwelling place of the soul, or life.
  10. A hinged device allowing for the easy folding of a mast 90 degrees from perpendicular, as for transporting the boat on a trailer, or passing under a bridge.
TABERNACLE verb
  1. To dwell; to abide for a time.

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