Cryptic crossword clue
Sacred book in case 5

The most common and most likely answer to this crossword clue is the 5 letter word BLEST

I've seen this crossword clue in The Guardian
B
L
E
S
T

More clues leading to the result BLEST

Buddy explains!

The straight part
We know that "Sacred" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sacred = blest.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BLEST mean?

BLEST adjective
  1. Having divine aid, or protection, or other blessing.
  2. A title indicating the beatification of a person, thus allowing public veneration of those who have lived in sanctity or died as martyrs.
  3. Held in veneration; revered.
  4. Worthy of worship; holy.
  5. An intensifier; damned.

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