Cryptic crossword clue
Sadly, Dr Kate’s gloomiest 7

The most common and most likely answer to this crossword clue is the 7 letter word DARKEST

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Buddy explains!

The straight part
We know that "gloomiest" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case gloomiest = darkest.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DARKEST mean?

DARKEST adjective
  1. Having an absolute or (more often) relative lack of light.
  2. (of colour) Dull or deeper in hue; not bright or light.
  3. Hidden, secret, obscure.
  4. Without moral or spiritual light; sinister, malign.
  5. Conducive to hopelessness; depressing or bleak.
  6. Lacking progress in science or the arts; said of a time period.
  7. With emphasis placed on the unpleasant aspects of life; said of a work of fiction, a work of nonfiction presented in narrative form or a portion of either.

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