The most common and most likely answer to this crossword clue is the 6 letter word DEMISE
D
E
M
I
S
E
More clues leading to the result DEMISE
- Failure of half the Home Counties
- End of old EMI’s empire
- Death leads to half empty senate
- Ending with half a point — Europe’s first
- Passing medium-dry champagne — not cold
- End of all but the last of medium-dry wine
- Death of half followed by a quarter?
- Sadly I seem resigned in the end to failure
- See dim bats passing
- Passing some trees, I meditate, looking west
Buddy explains!

The straight part
We know that "failure" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case failure = demise.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DEMISE mean?
DEMISE noun- The conveyance or transfer of an estate, either in fee for life or for years, most commonly the latter.
- Transmission by formal act or conveyance to an heir or successor; transference; especially, the transfer or transmission of the crown or royal authority to a successor.
- Death.
- The end of something, in a negative sense; downfall.
- To give.
- To convey, as by will or lease.
- To transmit by inheritance.
- To pass by inheritance.
- To die.