Cryptic crossword clue
Safety practice, case of choice blocking device 13

The most common and most likely answer to this crossword clue is the 13 letter word CONTRACEPTION

I've seen this crossword clue in The Guardian
C
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Buddy explains!

The straight part
We know that "Safety practice" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case safety practice = contraception.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

Crossword Answer definitions

CONTRACEPTION noun
  1. The use of a device or procedure to prevent conception as a result of sexual activity.

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