Cryptic crossword clue
Sage's wife missing after couple set out separately 7

The most common and most likely answer to this crossword clue is the 7 letter word ITEMISE

I've seen this crossword clue in The Times
I
T
E
M
I
S
E


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The straight part
We know that "set out separately" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case set out separately = itemise.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ITEMISE mean?

ITEMISE verb
  1. To state in items, or by particulars

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