The most common and most likely answer to this crossword clue is the 6 letter word ABDABS
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More clues leading to the result ABDABS
Buddy explains!

The straight part
We know that "anxiety" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case anxiety = abdabs.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ABDABS mean?
ABDABS noun- Extreme nervousness or anxiety; terror; heebie-jeebies.