The most common and most likely answer to this crossword clue is the 6 letter word SEAMEN
I've seen this crossword clue in The Times
S
E
A
M
E
N
Buddy explains!

The straight part
We know that "Sailors" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sailors = seamen.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SEAMEN mean?
SEAMEN noun- A mariner or sailor, one who mans a ship. Opposed to landman or landsman.
- A person of the lowest rank in the Navy, below able seaman.
- An enlisted rate in the United States Navy and United States Coast Guard, ranking below petty officer third class and above seaman apprentice.
- A merman; the male of the mermaid.