Cryptic crossword clue
Saint and philosopher who won’t give up? 6

The most common and most likely answer to this crossword clue is the 6 letter word STAYER

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "who won’t give up" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case who won’t give up = stayer.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does STAYER mean?

STAYER noun
  1. One who, or that which, upholds or supports; a prop.
  2. One who, or that which, stays, stops, or restrains.
  3. An athlete, horse, etc. with staying power.

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