The most common and most likely answer to this crossword clue is the 11 letter word SEGREGATION
I've seen this crossword clue in The Daily Telegraph
S
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Buddy explains!

The straight part
We know that "discrimination" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case discrimination = segregation.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does SEGREGATION mean?
SEGREGATION noun- The setting apart or separation of things or people, as a natural process, a manner of organizing people that may be voluntary or enforced by law.
- The setting apart in Mendelian inheritance of alleles, such that each parent passes only one allele to its offspring.
- Separation from a mass, and gathering about centers or into cavities at hand through cohesive or adhesive attraction or the crystallizing process.
- (public policy) The separation of people (geographically, residentially, or in businesses, public transit, etc) into racial or other categories (e.g. religion, sex).
- The separation of people (geographically, residentially, or in businesses, public transit, etc) into various categories which occurs due to social forces (culture, etc).
- The separation of a pair of chromatids or chromosomes during mitosis and meiosis