The most common and most likely answer to this crossword clue is the 6 letter word RETAIL
I've seen this crossword clue in The Times
R
E
T
A
I
L
More clues leading to the result RETAIL
- High Street activity that is limited about to come to the fore?
- Sale to make good Eeyore's loss?
- Market two films screened by opposite sides
- Trading in Australia terrible, as viewed from down under?
- Pretax bill no case for selling
- Sell dog again
- Kind of therapy needed by one that’s been docked?
- Sell right Yorkshire bitter, I’d say
- About to pursue sale of goods to the consumer
- Provide new final bit to trading activity?
Buddy explains!

The straight part
We know that "Sale" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sale = retail.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does RETAIL mean?
RETAIL noun- The sale of goods directly to the consumer, encompassing the storefronts, mail-order, websites, etc., and the corporate mechanisms, branding, advertising, etc. that support them.
- Retail price; full price; an abbreviated expression, meaning the full suggested price of a particular good or service, before any sale, discount, or other deal.
- To sell at retail, or in small quantities directly to customers.
- To sell secondhand, or in broken parts.
- To repeat or circulate (news or rumours) to others.
- Of or relating to the (actual or figurative) sale of goods or services directly to individuals.
- Direct to consumers, in retail quantities, or at retail prices.