The most common and most likely answer to this crossword clue is the 9 letter word WISECRACK
I've seen this crossword clue in The Times
W
I
S
E
C
R
A
C
K
More clues leading to the result WISECRACK
- Sally is on drugs, after whiskey
- Funny group of women like some wine on shelf
- We must accept one's attempt to make joke
- Old comedian to attempt joke
- Funny straight man split
- Dry artist in Scottish town making joke
- One half of comedy duo prior to expert joke
- Knowing excellent gag
- With one second, frame funny remark
Buddy explains!

The straight part
We know that "Sally" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sally = wisecrack.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does WISECRACK mean?
WISECRACK noun- A witty or sarcastic comment or quip.
- To make a sarcastic, flippant, or sardonic comment.