Cryptic crossword clue
Sane boys upset with a source of protein 8

The most common and most likely answer to this crossword clue is the 8 letter word SOYBEANS

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Buddy explains!

The straight part
We know that "source of protein" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case source of protein = soybeans.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SOYBEANS mean?

SOYBEANS noun
  1. A legume plant (Glycine max), commonly cultivated for human and animal consumption and as a nitrogen-fixing ground cover.
  2. The edible seed of this plant.

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