Cryptic crossword clue
Sap from lettuce hearts 4

The most common and most likely answer to this crossword clue is the 4 letter word COSH

I've seen this crossword clue in The Daily Telegraph
C
O
S
H


Buddy explains!

The straight part
We know that "Sap" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sap = cosh.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does COSH mean?

COSH noun
  1. A weapon made of leather-covered metal similar to a blackjack.
  2. A blunt instrument such as a bludgeon or truncheon.
  3. The cane.
COSH verb
  1. To strike with a weapon of this kind.
COSH adjective
  1. Cosy; snug

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