Cryptic crossword clue
Satirical writer left on journey, finally, with expedition 7

The most common and most likely answer to this crossword clue is the 7 letter word SWIFTLY

I've seen this crossword clue in The Sunday Telegraph
S
W
I
F
T
L
Y

Buddy explains!

The straight part
We know that "with expedition" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case with expedition = swiftly.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SWIFTLY mean?

SWIFTLY adverb
  1. In a swift manner; quickly; with quick motion or velocity; fleetly.

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