The most common and most likely answer to this crossword clue is the 12 letter word REHABILITATE
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More clues leading to the result REHABILITATE
Buddy explains!

The straight part
We know that "Save" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case save = rehabilitate.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does REHABILITATE mean?
REHABILITATE verb- To restore (someone) to their former state, reputation, possessions, status etc.
- To vindicate; to restore the reputation or image of (a person, concept etc.).
- To return (something) to its original condition.
- To restore or repair (a vehicle, building); to make habitable or usable again.
- To restore to (a criminal etc.) the necessary training and education to allow for a successful reintegration into society; to retrain.
- To return (someone) to good health after illness, addiction etc.
- To go through such a process; to recover.