Cryptic crossword clue
School of 26 rejecting big-selling single about to be No 1 7

The most common and most likely answer to this crossword clue is the 7 letter word GNOSTIC

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Buddy explains!

The straight part
We know that "School of 26" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case school of 26 = gnostic.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does GNOSTIC mean?

GNOSTIC noun
  1. A believer in Gnosticism
GNOSTIC adjective
  1. Of, or relating to, intellectual or spiritual knowledge
  2. Of, or relating to Gnosticism
GNOSTIC adjective
  1. Knowing; wise; shrewd

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