Cryptic crossword clue
Scientist ordered to abstain initially refused 8

The most common and most likely answer to this crossword clue is the 8 letter word BOTANIST

I've seen this crossword clue in The Guardian
B
O
T
A
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T


Buddy explains!

The straight part
We know that "Scientist" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case scientist = botanist.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BOTANIST mean?

BOTANIST noun
  1. A person engaged in botany, the scientific study of plants.

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