The most common and most likely answer to this crossword clue is the 5 letter word WRING
I've seen this crossword clue in The Times
W
R
I
N
G
More clues leading to the result WRING
Buddy explains!

The straight part
We know that "Screw" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case screw = wring.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does WRING mean?
WRING noun- A powerful squeezing or twisting action.
- Pain or distress.
- To squeeze or twist (something) tightly so that liquid is forced out. See also wring out.
- To extract (a liquid) from something wet, especially cloth, by squeezing and twisting it.
- To obtain (something from or out of someone or something) by force.
- To draw (something from or out of someone); to generate (something) as a response.
- To hold (something) tightly and press or twist.
- To cause pain or distress to (someone / one's heart, soul, etc.).
- To slide two ultraflat surfaces together such that their faces bond.
- To twist, as if in pain.
- To give an incorrect meaning to (words, teachings, etc.).
- To subject (someone) to extortion; to afflict or oppress in order to enforce compliance.
- To bend or strain out of its position.
- A device for pressing or compressing, especially for cider.