Cryptic crossword clue
Sealing cracks in air-conditioning, result is soothing 9

The most common and most likely answer to this crossword clue is the 9 letter word ANALGESIC

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "soothing" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case soothing = analgesic.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ANALGESIC mean?

ANALGESIC noun
  1. Any medicine, such as aspirin, that reduces pain, especially without inducing a loss of other sensation. (Contrast anesthetic.)
ANALGESIC adjective
  1. (pharmaceutical effect) Of or relating to analgesia; anodyne.

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